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| | All | Control | Case |
|---|
| N(%) or Mean (STD) | N(%) or Mean (STD) | N(%) or Mean (STD) |
|---|
| All participants | 394 (100) | 197 (100) | 197 (100) |
| Menopausal status and age at menopause at baseline |
| Pre-menopausal | 78 (19.8) | 39 (19.8) | 39 (19.8) |
| Post-menopausal | 316 (80.2) | 158 (80.2) | 158 (80.2) |
| Menopausal status and age at menopause at case’s date of diagnosis |
| Pre-menopausal | 3 (0.8) | 2 (1.0) | 1 (0.5) |
| Post-menopausal | 192 (48.7) | 99 (50.3) | 93 (47.2) |
| Age (years) at baseline | 56.3 (6.2) | 56.3 (6.2) | 56.3 (6.2) |
| Age (years) at case’s date of diagnosis | 68.4 (6.2) | 68.4 (6.2) | 68.4 (6.2) |
| BMI (kg/m2) at baseline |
| < 25 | 279 (70.8) | 136 (69.0) | 136 (69.0) |
| ≥ 25 | 115 (29.2) | 61 (31.0) | 61 (31.0) |
| BMI (kg/m2) at case’s date of diagnosis |
| < 25 | 261 (66.2) | 127 (64.5) | 134 (68.0) |
| ≥ 25 | 133 (33.8) | 70 (35.5) | 63 (32.0) |
| Total plasma lipid content (ng/L) | 5.4 (0.8) | 5.4 (0.9) | 5.4 (0.8) |
| Smoking status at baseline |
| Never | 192 (48.7) | 90 (45.7) | 102 (51.8) |
| Ever | 202 (51.3) | 107 (54.3) | 95 (48.2) |
| Physical activity (metabolic equivalent tasks (MET)-hour/week) at baseline |
| < 35 | 202 (51.3) | 100 (50.8) | 102 (51.8) |
| ≥ 35 | 192 (48.7) | 97 (49.2) | 95 (48.2) |
| Education level at baseline |
| < BAC | 39 (9.9) | 22 (11.2) | 17 (8.6) |
| BAC to BAC + 2 | 192 (48.7) | 98 (49.7) | 94 (47.7) |
| ≥ BAC + 2 | 163 (41.4) | 77 (39.1) | 86 (43.7) |
| Personal history of benign breast disease at baseline |
| No | 250 (63.5) | 135 (68.5) | 115 (58.4) |
| Yes | 144 (36.5) | 62 (31.5) | 82 (41.6) |
| Family history of breast cancer |
| None | 281 (71.3) | 146 (74.1) | 135 (68.5) |
| In first-degree relatives | 61 (15.5) | 31 (15.7) | 30 (15.2) |
| In extended relatives | 52 (13.2) | 20 (10.2) | 32 (16.3) |
| Parity and age at first full-term pregnancy (FFTP) |
| No children | 57 (14.5) | 22 (11.2) | 35 (17.8) |
| 1 or 2 children and < 30 years old at FFTP | 194 (49.2) | 97 (49.2) | 97 (49.2) |
| ≥ 3 children and < 30 years old at FFTP | 108 (27.4) | 62 (31.5) | 46 (23.4) |
| ≥ 30 years old at FFTP | 35 (8.9) | 16 (8.1) | 19 (9.6) |
| Total breastfeeding duration |
| Never | 152 (38.6) | 79 (40.1) | 73 (37.1) |
| ≤ 6 months | 164 (41.6) | 85 (43.1) | 79 (40.1) |
| > 6 months | 78 (19.8) | 33 (16.8) | 45 (22.8) |
| Age at menarche |
| < 13 years | 178 (45.2) | 95 (48.2) | 83 (42.1) |
| ≥ 13 years | 216 (54.8) | 102 (51.8) | 114 (57.9) |
| Current use of menopausal hormone therapy at baseline |
| No | 234 (59.7) | 119 (60.7) | 115 (58.7) |
| Yes | 158 (40.1) | 77 (39.1) | 81 (41.1) |
| Use of oral contraceptives at baseline |
| Never | 150 (38.1) | 79 (40.1) | 71 (36.0) |
| Ever | 244 (61.9) | 118 (59.9) | 126 (64.0) |
| Adherence score to the Healthy dietary pattern |
| < median | 197 (50.0) | 89 (45.2) | 108 (54.8) |
| > median | 197 (50.0) | 108 (54.8) | 89 (45.2) |
| Adherence score to the Western dietary pattern |
| < median | 197 (50.0) | 98 (49.7) | 99 (50.3) |
| > median | 197 (50.0) | 99 (50.3) | 98 (49.7) |
